Rheumatoid arthritis Causes, symptoms, treatment

Rheumatoid arthritis >Causes, symptoms, treatment

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What is Rheumatoid arthritis:-

  • Rheumatoid arthritis is an autoimmune disorder that causes symmetrical polyarthritis.
  • Arthritis is an inflammation of the joints.
  • Rheumatoid arthritis awareness day is celebrated on 2nd Feb.
  • Rheumatoid arthritis is a most common systemic inflammatory disease characterized by symmetrical joint involvement.

Rheumatoid arthritis Definition 

  • Rheumatoid arthritis is a chronic autoimmune disorder that include inflammation in the membrane lining of the joint and produce an inflammatory synovitis.
  • Rheumatoid arthritis generally involves small, peripheral and systemic or non-weight wear joints.
  • Commonly prevalence between the age of 30 – 50 years.

Cause of Rheumatoid arthritis

  • Idiopathic
  • Genetic factors
  • Environmental exposure
  • Immunological factor
  • Autoimmune disorder
  • Endocrine imbalance
  • Inflamed synovium
  • Tumour necrosis factor
  • DM, obesity
  • Lack of exercise
  • Vitamin D deficiency
  • Smoking
  • Bacterial and fungal infection
  • Antigen dependent activation of T- lymphocytes.
  • Metabolic imbalance.

Pathophysiology of Rheumatoid arthritis

Cause / immunological / autoimmune

Inflammation of synovial membrane of joint

Antigen and antibody reaction

Damage the articular cartilage

More production of granular tissue and edema

Decrease joint mobility

Deformity.

Stage of Rheumatoid Arthritis

Stage – I 

– Preclinical stage

 Non sign symptoms

– Increased ESR, C – reactive protein.

Stage II

  • Synovitis stage involves inflammation in the synovial membrane.
  • Show sign symptoms.
  • ADL affects.

Stage III

  • Destruction stage
  • Daily living activity affect
  • Both bones rub together and cause pain and swelling.

Stage IV

  • Deformity stage
  • End stage of rheumatoid arthritis
  • Loss of joint functions.

Sign and Symptoms of Rheumatoid arthritis 

  • Swelling and edema in the joints.
  • Morning joint stiffness.
  • Sever pain
  • Tenderness or redness
  • Deformity of joints ( loss of anatomy )
  • Reduce range of motion
  • Muscles pain
  • Rheumatoid nodules
  • Low grade fever
  • Fatigue and weight loss
  • Swan neck deformity
  • Polyarthritis and joint warmth.

Diagnosis of Rheumatoid arthritis

  • History collection and physical examination.
  • Joint x-ray ( show deformities )
  • Blood test – increase ESR, increased C reactive protein.
  • CT scan and MRI.
  •  Anti citrullinated protein antibodies (ACPAs).
  • History of infection.

Treatment of Rheumatoid arthritis

  • NSAID (non-steroidal anti-inflammatory drugs) and Aspirin used for pain.
  • Corticosteroids drugs – prednisolone (anti-inflammatory)
  • Topical analgesics (zostrix)
  • Immunosuppressive agents – methotrexate
  • Antirheumatic drugs – D. Penicillin
  • Chloroquine.
  • Disease-modifying ant rheumatic drugs (DMARD).

Surgical Management

  1. Arthroplasty – joint replacement surgery.
  2. Arthroscopy – is a surgical procedure on a joint to examine and treatment of damaged tissue by using arthro.
  3. Synovectomy – remove inflamed joints tissues.

Nursing Management  

  • Nurses monitor vital signs and joint immobility.
  • Assess small and peripheral joints are affected.
  • Assess patient range of motion.
  • Help to reduce morning joint stiffness, provide hot tea and hot bath.
  • Nurses provide a variety of comfort levels.
  • Provide rest, heat and cold application of message to reduce pain.
  • The Administrator prescribed medication.
  • Nurses encourage patients to verbalize feelings about pain and stiffness.
  • Identify causing emotional and physical factors that cause fatigue.
  • Nurses encourage independence in mobility or activity and assist them.
  • Nurse conduct counselling for self-care activity.
  • Provide physiological and emotional support.
  • Nurses provide health education.

Key Points

  1. Inflammation in the joints – Arthritis.
  2. Autoimmune joint disorder involves synovitis – Rheumatoid arthritis.
  3. Rheumatoid arthritis is more severe in – Women.
  4. Which type of joints are involved in rheumatic arthritis – Non weight wear joints.
  5. Which stage of rheumatoid arthritis involves the deformity – Stage IV.
  6. In which disorder is the swan neck deformity seen – Rheumatoid arthritis.
  7. Surgical joint replacement – Arthroplasty.
  8. Morning joint stiffness reduced by – Hot tea and hot bath.
  9. Surgical removal of infected joint tissue – Synovectomy.
  10. Rheumatoid arthritis deformity assessed by – Radiological examination (x-ray).
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